SigIntSigInt is a command-line software tool that can rank mammalian proteins/genes | |
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SigInt Ranking & Summary
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- License:
- Freeware
- Publisher Name:
- Mount Sinai School of Medicine Iyengar Lab
- File Size:
- 341 KB
SigInt Tags
SigInt Description
SigInt is a command-line software utility that can be used to find and rank mammalian proteins/genes that specifically and significantly interact with a list of proteins/genes in context of a background mammalian signalome and interactome networks. The inputs to the program are: · a seed list of human Entrez Gene gene symbols, · a background networks in SIG format, and · a name for the output file (web-page file name with the htm extension) SigInt outputs a sorted list of genes/proteins that interacts with components from the seed list. These components are sorted by a z-score that measures the specificity of these intermediate components to interact with the genes/proteins from the seed list.
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