TangleSolve Site-specific recombination analysis made easy.
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analyzer analysis Analyze Site Specific Browser Site Analysis Intracodon Recombination Recombination recombination rate meiotic recombination hotspot recombination recombination analysis

TangleSolve Description

TanlgeSolve is a simple Java application designed to be used in the analysis of site-specific recombination. Site-specific recombination is mediated by the protein site-specific recombinase and is important because of its key role in a wide variety of biological processes such as: deoxyribose nucleic acid (DNA) rearrangement, integration and excursion of viral DNA into and out of a host genome, and resolution of multimeric DNA molecules to allow proper segregation at cell division. This program is concerned with site-specific recombinases that converts unknotted circular DNA substrates into knotted or linked DNA of specific topology. TangleSolve assumes that substrates and products of recombination are 4-plats because most knots and links seen in biology are 4-plat (or 2-bridge knots and links).

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